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It is the primary driver of autoimmune diseases like Hashimoto’s Thyroiditis

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Recent evidence using several public datasets from The Cancer Genome Atlas (TCGA), Kyoyo Encyclopedia of Genes and Genomes (KEGG), AmiGO ( CHKB , and phosphatidylethanolamine N-methyltransferase, PEMT ) as key genes involved in the pathogenesis of human colorectal cancer (220, 221)