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For example, E50K mutated OPTN induced impairment of autophagy that led to cell death in RGC-5 cell lines 28 , and rapamycin, an autophagic inducer, protected RGCs in E50K OPTN overexpressed rats in vivo 29
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Elevated expression of toll-like receptor 4 is associated with NADPH oxidase-induced oxidative stress in B cells of children with autism
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