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Back to Journals » Journal of Pain Research » Volume 12 Acetyl-L-carnitine in painful peripheral neuropathy: a systematic review Authors Di Stefano G, Di Lionardo A, Galosi E , Truini A, Cruccu G Received 9 October 2018 Accepted for publication 28 January 2019 Published 26 April 2019 Volume 2019:12 Pages 1341—1351 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor E Alfonso Romero-Sandoval Giulia Di Stefano, Andrea Di Lionardo, Eleonora Galosi, Andrea Truini, Giorgio Cruccu Department of Human Neuroscience, Sapienza University, Rome, Italy Abstract: Acetyl-L-carnitine (ALC) has shown a neuroprotective effect in patients with peripheral neuropathies of different etiologies

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Fasting glucose, triglycerides, and waist circumference are the standard clinical markers of metabolic syndrome, and researchers use these peripheral measures as observable proxies for the central insulin resistance that is harder to measure directly in living patients [2,4]