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Histone deacetylases including SIRT1, interact with STAT3 and negatively regulate its transcriptional activity by deacetylating critical lysine residues (Nie et al., 2009)
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Lipid metabolism Lipidomic studies have shown that phosphatidylethanolamines (PEs) with arachidonic acid (AA) or its derivative adrenergic acid (AdA) are the key phospholipids for oxidation, and their peroxidation is considered a significant driver of ferroptosis [19, 21]
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